Understand the essential principles of toxicology and how poisons affect the human body with this accessible and engaging summary

• General Principles of Toxicology
• Disposition of Toxicants
• Nonorgan-directed Toxicity
• Target Organ Toxicity
• Toxic Agents
• Environmental Toxicology
• Applications of Toxicology

Casarett & Doull's Essentials of Toxicology is an easy-to-absorb distillation of the major principles and concepts that were presented in depth in Casarett & Doull's Toxicology: The Basic Science of Poisons, Eighth Edition, the field's gold-standard text.

Presented in full color, the book concisely describes the science of toxicology, and includes important concepts from anatomy, physiology, and biochemistry to facilitate the understanding of the principles and mechanisms of toxicant action on specific organ systems. A summary of key points at the beginning and review questions at the end of each chapter help you study, understand, and memorize the material.

Reflecting the expertise of more than sixty renowned contributors, Casarett & Doull's Essentials of Toxicology is logically divided into seven sections:

Succinct and comprehensive, there is no better text for gaining an understanding of essential principles, toxicokinetics, how toxic effects are passed on to succeeding generations, how each body system responds to poisons, and the specific effects of a wide range of toxic agents than Casarett & Doull's Essentials of Toxicology.

Table of contents

1 GENERAL PRINCIPLES OF TOXICOLOGY

1. History and Scope of Toxicology
2. Principles of Toxicology
3. Mechanisms of Toxicity
4. Risk Assessment

2 DISPOSITION OF TOXICANTS

5. Absorption, Distribution, and Excretion of Toxicants
6. Biotransformation of Xenobiotics
7. Toxicokinetics

3 NONORGAN-DIRECTED TOXICITY

8. Chemical Carcinogenesis
9. Genetic Toxicology
10. Developmental Toxicology

4 TARGET ORGAN TOXICITY

11. Toxic Responses of the Blood
12. Toxic Responses of the Immune System
13. Toxic Responses of the Liver
14. Toxic Responses of the Kidney
15. Toxic Responses of the Respiratory System
16. Toxic Responses of the Nervous System
17. Toxic Responses of the Ocularand Visual System
18. Toxic Responses of the Heart and Vascular System
19. Toxic Responses of the Skin
20. Toxic Responses of the Reproductive System
21. Toxic Responses of the Endocrine System

5 TOXIC AGENTS

22. Toxic Effects of Pesticides
23. Toxic Effects of Metals
24. Toxic Effects of Solvents and Vapors
25. Toxic Effects of Radiation
26. Toxic Effects of Terrestrial Animal
27. Toxic Effects of Plants, Fungi, and Algae

6 ENVIRONMENTAL TOXICOLOGY

28. Air Pollution
29. Ecotoxicology

7 APPLICATIONS OF TOXICOLOGY

30. Food Toxicology
31. Analytic/Forensic Toxicology
32. Clinical Toxicology
33. Occupational ToxicologyAuthor

Curtis Klaassen PhD Professor and Chair, Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center.

John Watkins, III PhD Professor of Pharmacology and Toxicology, The Medical Sciences Program.